One Hundred Years of Statistical Developments in Animal Breeding

Written by: Stephen Hsu

Primary Source: Information Processing

This nice review gives a history of the last 100 years in statistical genetics as applied to animal breeding (via Andrew Gelman).

One Hundred Years of Statistical Developments in Animal Breeding
(Annu. Rev. Anim. Biosci. 2015. 3:19–56 DOI:10.1146/annurev-animal-022114-110733)

Statistical methodology has played a key role in scientific animal breeding. Approximately one hundred years of statistical developments in animal breeding are reviewed. Some of the scientific foundations of the field are discussed, and many milestones are examined from historical and critical perspectives. The review concludes with a discussion of some future challenges and opportunities arising from the massive amount of data generated by livestock, plant, and human genome projects.

I’ve gone on and on about approximately additive genetic architecture for many human traits. These arguments are supported by the success of linear predictive models in animal breeding. But who has time to read literature outside of human genetics? Who has time to actually update priors in the face of strong evidence? ;-)

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Stephen Hsu
Stephen Hsu is vice president for Research and Graduate Studies at Michigan State University. He also serves as scientific adviser to BGI (formerly Beijing Genomics Institute) and as a member of its Cognitive Genomics Lab. Hsu’s primary work has been in applications of quantum field theory, particularly to problems in quantum chromodynamics, dark energy, black holes, entropy bounds, and particle physics beyond the standard model. He has also made contributions to genomics and bioinformatics, the theory of modern finance, and in encryption and information security. Founder of two Silicon Valley companies—SafeWeb, a pioneer in SSL VPN (Secure Sockets Layer Virtual Private Networks) appliances, which was acquired by Symantec in 2003, and Robot Genius Inc., which developed anti-malware technologies—Hsu has given invited research seminars and colloquia at leading research universities and laboratories around the world.