Behold, the Super Cow

Hmm… how do they compute the Net Merit and GTPI? (But, but, what about all of that missing heritability?) See also Applied genomics: the genetic “super cow” Genomic prediction: no bull. Attention climate virtue signalers: more efficient cows produce less methane per liter of milk! Drink milk from genetically engineered cows :-) Tweet

23andme

I’m in Mountain View to give a talk at 23andMe. Their latest funding round was $250M on a (reported) valuation of $1.5B. If I just add up the Crunchbase numbers it looks like almost half a billion invested at this point… Slides: Genomic Prediction of Complex Traits Abstract: We apply methods from Compressed Sensing (L1-penalized regression; Donoho-Tanner …

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Thread Safety

As I noted in yesterday’s post, one of the major changes associated with the new “generic” callback structure in CPLEX is that users now bear the responsibility of making their callbacks thread-safe. As I also noted yesterday, this is pretty new stuff for me. So I’m going to try to share what I know about thread …

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CPLEX 12.8: Generic Callbacks

IBM is getting ready to release CPLEX 12.8, and I had the opportunity to attend a presentation about by Xavier Nodet at the 2017 INFORMS annual meeting. Here are links to two presentations by Xavier: CPLEX Optimization Studio 12.8 – What’s New and CPLEX 12.8 – the Generic Callback. As with any new release, there …

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The Philosophers’ Way

Sometimes we forget … forget to take a break, forget to get outside, and forget to reflect on our individual and collective pasts. After an intense three days of talks at EMBO—hearing about exciting work by diverse and superb biologists in 13-minute chunks (plus Q&A); seeing dear friends Santiago Elena, Sebastian Bonhoeffer, and Roy Kishony; …

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Steven Weinberg: What’s the matter with quantum mechanics?

In this public lecture Weinberg explains the problems with the two predominant interpretations of quantum mechanics, which he refers to as Instrumentalist (e.g., Copenhagen) and Realist (e.g., Many Worlds). The term “interpretation” may be misleading because what is ultimately at stake is the nature of physical reality. Both interpretations have serious problems, but the problem …

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Survival of the Steepest

Most textbooks tell you that the evolutionary process is really quite simple: three rules are all that’s necessary: inheritance, variation, and selection. It is indeed true that these three rules are all that’s needed for evolution to occur, but that does not mean that the evolutionary process is simple. In fact, quite the opposite. Real systems evolve in …

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Is there such a thing as “white hat” research ethics violations?

A couple of weeks ago, I posted about some of the ethical dilemmas involved in using public data for research, using an example of facial recognition researchers who used YouTube videos of people undergoing hormone replacement therapy to improve their algorithms’ ability to recognize faces from pre- and post-transition. Since reading that article, I’ve seen the occasional …

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Public data and digital research ethics

The Verge recently posted an article that highlights some of the ethical dilemmas involved in collecting publicly-available data for research purposes. The article begins by describing the work of a researcher working on facial recognition of people before and after hormone replacement therapy: On YouTube, he found a treasure trove. Individuals undergoing HRT often document their progress …

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Meanwhile, down on the Farm

The Spring 2017 issue of the Stanford Medical School magazine has a special theme: Sex, Gender, and Medicine. I recommend the article excerpted below to journalists covering the Google Manifesto / James Damore firing. After reading it, they can decide for themselves whether his memo is based on established neuroscience or bro-pseudoscience. Perhaps top Google …

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In the matter of James Damore, ex-Googler

James Damore, Harvard PhD* in Systems Biology, and (until last week) an engineer at Google, was fired for writing this memo: Google’s Ideological Echo Chamber, which dares to display the figure above. Here is Damore’s brief summary of his memo (which contains many citations to original scientific research), and the conclusion: Google’s political bias has …

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A day in the field

3:00 a.m. My alarm goes off. I open my eyes and see the Heilongjiang sun starting to rise. I close my eyes just for a minute more… (Editor’s note – China, while geographically spanning five time zones, follows only one for unity. That means far eastern locales like Heilongjiang see daybreak early.) 3:15 a.m. My …

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Robots taking our jobs

The figures below are from the recent paper Robots and Jobs: Evidence from US Labor Markets, by Acemoglu and Restrepo. VoxEU discussion: … Estimates suggest that an extra robot per 1000 workers reduces the employment to population ratio by 0.18-0.34 percentage points and wages by 0.25-0.5%. This effect is distinct from the impacts of imports, …

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Natural Selection and Body Shape in Eurasia

Prior to the modern era of genomics, it was claimed (without good evidence) that divergences between isolated human populations were almost entirely due to founder effects or genetic drift, and not due to differential selection caused by disparate local conditions. There is strong evidence now against this claim. Many of the differences between modern populations …

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Don’t Touch the Computer

Under what circumstances should humans override algorithms? From what I have read I doubt that a hybrid team of human + AlphGo would perform much better than AlphaGo itself. Perhaps worse, depending on the epistemic sophistication and self-awareness of the human. In hybrid chess it seems that the ELO score of the human partner is …

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Genetic variation in Han Chinese population

Largest component of genetic variation is a N-S cline (phenotypic N-S gradient discussed here). Variance accounted for by second (E-W) PC vector is much smaller and the Han population is fairly homogeneous in genetic terms: …while we revealed East-to-West structure among the Han Chinese, the signal is relatively weak and very little structure is discernible …

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Memory Minimization

As I grow older, I’m starting to forget things (such as all the math I ever learned) … but that’s not the reason for the title of this post. A somewhat interesting question popped up on Mathematics StackExchange. It combines a basic sequencing problem (ordering the processing of computational tasks) with a single resource constraint …

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Super-human Relational Reasoning (DeepMind)

These neural nets reached super-human (better than an average human) performance on tasks requiring relational reasoning. See the short video for examples. A simple neural network module for relational reasoning https://arxiv.org/abs/1706.01427 Adam Santoro, David Raposo, David G.T. Barrett, Mateusz Malinowski, Razvan Pascanu, Peter Battaglia, Timothy Lillicrap (Submitted on 5 Jun 2017) Relational reasoning is a …

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Waves of grain

My car packed with too many clothes, an extremely terrified cat and a live Kombucha culture, I headed west to my summer field site. Oddly enough, my summer field site is also where I grew up. The endless waves of grain remind me of my labor-intensive childhood detasseling corn,1 walking beans2 and bucking bales.3  I …

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How the brain does face recognition

  This is a beautiful result. IIUC, these neuroscientists use the terminology “face axis” instead of (machine learning terminology) variation along an eigenface vector or feature vector. Scientific American: …using a combination of brain imaging and single-neuron recording in macaques, biologist Doris Tsao and her colleagues at Caltech have finally cracked the neural code for …

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Face Recognition applied at scale in China

The Chinese government is not the only entity that has access to millions of faces + identifying information. So do Google, Facebook, Instagram, and anyone who has scraped information from similar social networks (e.g., US security services, hackers, etc.). In light of such ML capabilities it seems clear that anti-ship ballistic missiles can easily target …

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Premature Obituaries

[T]he report of my death was an exaggeration. (Mark Twain, 1897) In a recent blog post, “Data Science Is Not Dead“, Jean-Francois Puget discussed and dissented with a post by Jeroen ter Heerdt titled “Data Science is dead.” Barring the possibility that Schroedinger shoved data science into a box and sealed it, both assertions cannot …

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Scientific Consensus on Cognitive Ability?

From the web site of the International Society for Intelligence Research (ISIR): a summary of the recent debate involving Charles Murray, Sam Harris, Richard Nisbett, Eric Turkheimer, Paige Harden, Razib Khan, Bo and Ben Winegard, Brian Boutwell, Todd Shackelford, Richard Haier, and a cast of thousands! ISIR is the main scientific society for researchers of …

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Climate Risk and AI Risk for Dummies

The two figures below come from recent posts on climate change and AI. Please read them. The squiggles in the first figure illustrate uncertainty in how climate will change due to CO2 emissions. The squiggles in the second figure illustrate uncertainty in the advent of human-level AI.   Many are worried about climate change because …

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Rise of the Machines: Survey of AI Researchers

These predictions are from a recent survey of AI/ML researchers. See SSC and also here for more discussion of the results. When Will AI Exceed Human Performance? Evidence from AI Experts Katja Grace, John Salvatier, Allan Dafoe, Baobao Zhang, Owain Evans Advances in artificial intelligence (AI) will transform modern life by reshaping transportation, health, science, …

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Epistemic Caution and Climate Change

I have not, until recently, invested significant time in trying to understand climate modeling. These notes are primarily for my own use, however I welcome comments from readers who have studied this issue in more depth. I take a dim view of people who express strong opinions about complex phenomena without having understood the underlying …

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